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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Join Pain And Protein Abnormalities

My 21 year old daughter has had joint pain for about 3 months. She has been tested for parovirus, inflammation, bacteria, ra factor and protein abnormalities among other tests. All have been negative Her gammaglobulin is 17... which is high. She is active, works out regularly, on a university rowing team, rock climbs and snowboards. We are wondering if there could be something as far as a connective tissue disorder. My family has a history of Reiters syndrome and post reactive arthritis. We are wondering what these results may mean?
Wed, 27 Aug 2014
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Internal Medicine Specialist,  's  Response
HI
Thanks for posting your query to Healthcaremagic .

I need more information on her symptoms .

1. What joints are paining ? ( Mention all )
2. Is the Joint pain continuous or is it intermittent ?
3. Is there any morning stiffness in joints which improves as the day progresses ?
4. Is there any tenderness / redness in the joints ?

Since you mentioned a family history of Reiters syndrome , is her eyes tested for Conjunctivits or uveitis . If not get it done . Any Urinary problems ?

I would want you to upload all the reports so that I can analyse them and advise you better.

The chance of Autoimmune disease/ Connective tissue disease is possible . I will advise necessary tests after seeing your previous reports .
As of raised gamma globulin is concerned there are many disease that can raise Gamma globulin . . Diseases that produce an increase in the gamma-globulin level include Hodgkin’s disease, malignant lymphoma, chronic lymphocytic leukemia, granulomatous diseases, connective tissue diseases, liver diseases, multiple myeloma, Waldenström’s macroglobulinemia, and amyloidosis.

So if not done I advise a Blood Protein Electrophoresis test for her .

Kindly revert back .
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Suggest Treatment For Join Pain And Protein Abnormalities

HI Thanks for posting your query to Healthcaremagic . I need more information on her symptoms . 1. What joints are paining ? ( Mention all ) 2. Is the Joint pain continuous or is it intermittent ? 3. Is there any morning stiffness in joints which improves as the day progresses ? 4. Is there any tenderness / redness in the joints ? Since you mentioned a family history of Reiters syndrome , is her eyes tested for Conjunctivits or uveitis . If not get it done . Any Urinary problems ? I would want you to upload all the reports so that I can analyse them and advise you better. The chance of Autoimmune disease/ Connective tissue disease is possible . I will advise necessary tests after seeing your previous reports . As of raised gamma globulin is concerned there are many disease that can raise Gamma globulin . . Diseases that produce an increase in the gamma-globulin level include Hodgkin’s disease, malignant lymphoma, chronic lymphocytic leukemia, granulomatous diseases, connective tissue diseases, liver diseases, multiple myeloma, Waldenström’s macroglobulinemia, and amyloidosis. So if not done I advise a Blood Protein Electrophoresis test for her . Kindly revert back .