Hi Welcome to healhcaremagic After going through your query I concluded that you developed early osteoarthritis of knee joint. You are taking orcerine Gm( Diacerine and glucosamine combination). These are disease modifying agents for osteochondritis of knee joints. These are to be taken regularly. For pain relief you can take analgesic such as ibuprofen whenever required. You can discuss your doctor about it. Hope your query get answered. If you have any clarification then please don t hesitate to write to us. I will be happy to answer your queries. You can also write to me directly on below link: https://www.bit.ly/askdrsudhirortho Wishing you good health. Take care.