Hi, My daughter has been suffering with osteonecrosis of the right and left tibula and fibula. Recently she had an MRI and unfortunately she now has it in her distal femers, also new lesions in the left tibula and fibula. According to most of the doctors and specialists we have seen she is a special case . It seems as if she is somewhat backwards in her condition, ie she bleeds easier when NOT on blood thinners than when on them. Her medical condition is eNOS T-786c and homozygote factor VIII and XI elevation. The latest recommendation is for her to be back on Xarelto and citrulline. We are looking for any recommendations of a cure and also any specialists in the northern CA. area. Thank you for your time Susan Cole