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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Preputium Clitoridis Lipoma

Hello. I have a tiny (3mm) preputium clitoridis lipoma. My brother was recently diagnosed with a very high grade paratesticular liposarcoma with metastatic disease to the lungs and numerous other local lesions. Should I have mine removed given family history and suspected Li-Fraumeni syndrome per family cancer risk assessment? I am 42 years old, 5'6", 150lb and in good health.
Mon, 9 May 2016
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General & Family Physician 's  Response
Hi thanks for contacting HCM...

Here your lipoma size very small and it should be excised....
Here chance of malignancy is less.....

As you have positive family history you can do genetic screening.....

P53 gene is tumour suppressor gene...
Its mutation called li fraumanin syndrome .
For that PCR or FISH testing can be done...

If that gene mutation present then chances of multiple tumour can be there and regular follow up needed.....

Take care....

Dr.Parth
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Suggest Treatment For Preputium Clitoridis Lipoma

Hi thanks for contacting HCM... Here your lipoma size very small and it should be excised.... Here chance of malignancy is less..... As you have positive family history you can do genetic screening..... P53 gene is tumour suppressor gene... Its mutation called li fraumanin syndrome . For that PCR or FISH testing can be done... If that gene mutation present then chances of multiple tumour can be there and regular follow up needed..... Take care.... Dr.Parth