Hi, I had gone through your question and understand your concerns.
It would have been great had I examined your uncle on my own.
WHat I can make out from your description is that your uncle may be suffering from chronic
pancreatitis with calcifications and dilated
pancreatic duct.
Chronic pancreatitis can be treated by medications like pancreatic enzymes like
creon and surgeries like Puestow's operation, Whipple's operation , distal
pancreatectomy depending on the percentage of
pancreas involved.
I would suggest you to write back to us with a more detailed history , a bit of O.T note , last CECT abdomen.
Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions.
Wishing your uncle's good health.