I have been suffering from major depression for years, why does ssri's, snri's, mao, trycyclics all fail? not until my MD tried Adderall, Ritalin then focalin have I experienced some relief? I have tried them all wellbutrin, nardil, paxil, Lexapro, celexa, remeron, Effexor, Prozac, ALL of them. Focalin totally erase my depression, not just covers it up, cures it! I say this in reference to the book by Russell Barkley PhD. Yet the stigma and difficulty is unbelievable! I don't mean to sound ignorant but the medical professionals need to get their head out of their ass and wake up! So many people can be cured that needlessly suffer, my brother is the same and can not get the medication, due to ignorance, any suggestions?