Welcome to HCM! I have gone through your question and it says that you are concerned about feeling of running thoughts sometimes..., you had anxiety and mild depression, and there is history of stroke in family. This presentation doesn t looks like anything related to organic brain syndrome, eg., stroke etc., so, don t worry.. This appears to be a symptom of mania...may be anxiety , but in anxiety one has more of worrying, disturbing thoughts and patient doesn t commonly come up with words of thoughts running ...this happens more with mania. In mania also patient can have comorbid anxiety... I think you are on some antidepressant/ anti anxiety for your past symptoms, and now it is likely that they made you go into mania.. I m not sure , but it is a very common cause of switch to mania from depression episode ( due to use of antidepressants ) . Had you mentioned the treatment you are currently on, it would have helped in giving you a correct reply. But one thing is certain that you should not ignore this symptoms and discuss it with your psychiatrist. Only after proper interviewing one can see what is happening and what medicine is to be given / or needs to be stopped. It is an easily controllable problem, so, do not panic at all. see your doctor. Hope this helps you Do feel free to ask more questions Dr. Manisha Gopal.