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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Used Diovam. Now Take Irbesar. Now Have Swelling In Legs, Ankles. Side Effect?

I was taking Diovam nd due to huge price increase for its generic the doctor gave me Irbesar/hctz 300-12.5.I started taking it last Monday and on Wednesday started breaking out on my legs and ankles swelling. Is his a side effect of this medication? If so do you have any suggestions for a different medication? My dr said this could no possibly cause this.
Tue, 27 Aug 2013
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General & Family Physician 's  Response
Hello,
Thanks for the query to H.C.M. Forum.
At present you are taking Irbesar/hctz ( irbesartan 300 mg+hydrochlorothiaze 12.5 mg) .
As you stated in your query that there develops swelling over legs & ankles ( both side).
Irbesartan itself causes myalgia , insomnia EDEMA , fatigue , urticaria.
On the other side Hydrochlorothiazide causes diuresis i.e. reduces edema ,so these are two contrary things ,but good for maintenance of Blood pressure .
In my opinion the drugs would adjust within 5-7 days , so wait.
Still you feel any thing wrong then consult your treating physician & get his opinion.
Good luck.
Dr. HET
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Used Diovam. Now Take Irbesar. Now Have Swelling In Legs, Ankles. Side Effect?

Hello, Thanks for the query to H.C.M. Forum. At present you are taking Irbesar/hctz ( irbesartan 300 mg+hydrochlorothiaze 12.5 mg) . As you stated in your query that there develops swelling over legs & ankles ( both side). Irbesartan itself causes myalgia , insomnia EDEMA , fatigue , urticaria. On the other side Hydrochlorothiazide causes diuresis i.e. reduces edema ,so these are two contrary things ,but good for maintenance of Blood pressure . In my opinion the drugs would adjust within 5-7 days , so wait. Still you feel any thing wrong then consult your treating physician & get his opinion. Good luck. Dr. HET