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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Vasculitis, Leg Bruises. On Leukeran. Blood Test Shows Platelet Count, WBC Count, CBC Done. Treatment?

hi,i have vasculitis and im being treated with leukeran. my recent blodd test showes my patelet count was 55.--also my white count was 1.5.m y dr. reduced my leukeran and treated me with 10 days of predisone. he had me repeat the cbc and my count came up to 66 and the white count to 2.5.i have a big bruise on my leg and im one of jehovahs witnesses and dont take blood . is there anything else i could do? my dr wont be in the office until monday.
Wed, 4 Sep 2013
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Rheumatologist,  's  Response
Hi. What i infer is that you have bone marrow suppression because of the drug leukeran which is being prescribed for your vasculitis, which i guess is under control as you havent mentioned about it. Drug induced bone marrow suppression usually recovers by itself when the offending agent is withdrawn or dose is reduced. Since your counts are improving, i think you just need to wait and watch your counts. There is no need to panic at present unless you have a spike of fever which could be dangerous. Also look at the absolute neutrophil counts, and this should be atleast 1000/cu mm. If less than this you may be prone to infection and may require injections to improve your neutrophil counts. But i guess for now you need not worry. Thank you.
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Vasculitis, Leg Bruises. On Leukeran. Blood Test Shows Platelet Count, WBC Count, CBC Done. Treatment?

Hi. What i infer is that you have bone marrow suppression because of the drug leukeran which is being prescribed for your vasculitis, which i guess is under control as you havent mentioned about it. Drug induced bone marrow suppression usually recovers by itself when the offending agent is withdrawn or dose is reduced. Since your counts are improving, i think you just need to wait and watch your counts. There is no need to panic at present unless you have a spike of fever which could be dangerous. Also look at the absolute neutrophil counts, and this should be atleast 1000/cu mm. If less than this you may be prone to infection and may require injections to improve your neutrophil counts. But i guess for now you need not worry. Thank you.