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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Repercussions Of Overdosing On Benadryl?

Hi, last night I took 2 Tylenol extra strength at 10:30 pm for a headache. I was having pretty bad allergies as well. so I took 2 offbrand Benadryl severe allergy & sinus headache (Meijer off-brand) at about 2:38 am. I believe the Tylenol extra strength contained about 500 mg of acetaminophen in each capsule. The offbrand Benadryl contains 325 mg of acetaminophen, 25 mg of diphenhydramine HCl, & 5 mg of Phenylephrine HCl in each capsule. Was this okay to do? I saw on the package later this morning on the offbrand allergy medicine that it says not to take with other drugs containing acetaminophen. I m worried that I may have taken too much in that time period because I m still really tired this afternoon.
Mon, 30 Mar 2020
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General Surgeon,  's  Response
Hello,

Though the intake of Benadryl with tylenol extra strength indicates above the normal range of recommended doses, there is no serious threat that one may be having life endangering effects. But beware of consumption of further over doses as that may lead to harm to liver as necrosis or else.

Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Bhagyesh V. Patel, General Surgeon
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What Are The Repercussions Of Overdosing On Benadryl?

Hello, Though the intake of Benadryl with tylenol extra strength indicates above the normal range of recommended doses, there is no serious threat that one may be having life endangering effects. But beware of consumption of further over doses as that may lead to harm to liver as necrosis or else. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Bhagyesh V. Patel, General Surgeon