Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.
Divalproex Sodium is used to treat certain types of seizures (
epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Divalproex Sodium is also used to treat the manic phase of
bipolar disorder (manic-depressive illness), and helps prevent
migraine headaches.
Rarely, this medication has caused serious (sometimes fatal) liver problems, usually within the first 6 months of starting treatment. Laboratory tests should be performed before you start treatment and periodically during treatment, especially within the first 6 months, to monitor this side effect.
The risk of serious liver problems is increased in children younger than 2 years, especially if they have an
inherited metabolic disorder, severe
seizure disorder with mental retardation , organic brain disease, or if they take more than one seizure medication. Talk with the doctor about the risks and benefits of using this medication in children younger than 2 years.
Due to an increased risk for liver problems, people with certain inherited metabolic disorders (such as Alpers-Huttenlocher syndrome) should not use this medication. Children younger than 2 years who might have these disorders should not use this medication. Children older than 2 years who might have these disorders should be closely monitored during treatment with Divalproex Sodium. Talk to your doctor for details.
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Khan Shoeb Mohammad Sher Mohammad