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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Side-effects Of Encorata Chrono Given For A Child S Hyperactivity?

Dear Doctor , My son of age 13yrs has been very hyper active and bold was taken for a therapy and the doctor has advised to take Encorata chrono 300 ,one tablet at night - which we had started since one month from now . Now my son complaints that he gets severe headache and drowsiness and feels tired in the evening and sometimes at day time too.We told this to the doctor who had advised not to stop the medicine but to continue and then gradually bring down the dose to half a tablet and later we can stop this it seems . My question is has this medicine started with any side effects in my son ?? Does this medicine has any side effects ?? Can we stop this medicine now since it gives other problems like drowsiness and tiredness ?? What type of patients are given such medicines ?? I understand from web sites that this medicine is banned through out the world due to side effects and active only in India & Sri lanka - is that true ??? Let me have a immediate reply pls Regards, Mathew Koshy Doha - Qatar .
Wed, 7 Jun 2017
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Pediatrician 's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

Divalproex Sodium is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Divalproex Sodium is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches.

Rarely, this medication has caused serious (sometimes fatal) liver problems, usually within the first 6 months of starting treatment. Laboratory tests should be performed before you start treatment and periodically during treatment, especially within the first 6 months, to monitor this side effect.

The risk of serious liver problems is increased in children younger than 2 years, especially if they have an inherited metabolic disorder, severe seizure disorder with mental retardation , organic brain disease, or if they take more than one seizure medication. Talk with the doctor about the risks and benefits of using this medication in children younger than 2 years.

Due to an increased risk for liver problems, people with certain inherited metabolic disorders (such as Alpers-Huttenlocher syndrome) should not use this medication. Children younger than 2 years who might have these disorders should not use this medication. Children older than 2 years who might have these disorders should be closely monitored during treatment with Divalproex Sodium. Talk to your doctor for details.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Khan Shoeb Mohammad Sher Mohammad
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What Are The Side-effects Of Encorata Chrono Given For A Child S Hyperactivity?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Divalproex Sodium is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures. Divalproex Sodium is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches. Rarely, this medication has caused serious (sometimes fatal) liver problems, usually within the first 6 months of starting treatment. Laboratory tests should be performed before you start treatment and periodically during treatment, especially within the first 6 months, to monitor this side effect. The risk of serious liver problems is increased in children younger than 2 years, especially if they have an inherited metabolic disorder, severe seizure disorder with mental retardation , organic brain disease, or if they take more than one seizure medication. Talk with the doctor about the risks and benefits of using this medication in children younger than 2 years. Due to an increased risk for liver problems, people with certain inherited metabolic disorders (such as Alpers-Huttenlocher syndrome) should not use this medication. Children younger than 2 years who might have these disorders should not use this medication. Children older than 2 years who might have these disorders should be closely monitored during treatment with Divalproex Sodium. Talk to your doctor for details. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Khan Shoeb Mohammad Sher Mohammad