I stopped taking 10mg lipitor in January 2010 as it made my muscles feel tired, and started taking 5mg lipitor again in June 2010 with CoenzymeQ10. I have not had muscle fatigue since, however, I notice that my big toenails both have pronounced rigding from about 3mm to their roots. The nails are smooth from 3mm outwards (the oldest growth). I have read that big toenails grow slowly and think that the change in their growth coincides with starting to take statins and CoQ10. I feel well otherwise, but should I be concerned about any other unwanted effects?