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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Signs Of Metastatic Liver Cancer?

my mother was diagosed with colon cancer and a colectomy was performed last year (May 2010). Biopsy showed a stage II cancer. Chemo was performed (6 months) intrvenous and oral (xeloda). She did some blood tests today and showed mildly elevated transaminases ( AST 43,1 IU/ml and ALT 70,7 IU/ml). Considering she takes Lipidil 200mg daily, does this mean metastatic liver cancer?
Tue, 5 May 2015
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Radiologist,  's  Response
Hi,
Thanks for writing in.

In patients who have colon cancer and those who have got surgery done, nearly half the patients will progress to have liver metastasis. Your mother has an early stage of cancer if it was stage 2 and therefore regular follow up is essential to pick up any metastasis if seen in the earliest stage during a follow up ultrasound scan or CT scan.

I can see that you have mentioned AST and ALT results but to tell the chances for a liver metastasis the alkaline phosphatase levels are more reliable. If alkaline phosphatase rises more than 12 units in 6 weeks then there is a higher chance of liver metastasis. Please do not worry.
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What Are The Signs Of Metastatic Liver Cancer?

Hi, Thanks for writing in. In patients who have colon cancer and those who have got surgery done, nearly half the patients will progress to have liver metastasis. Your mother has an early stage of cancer if it was stage 2 and therefore regular follow up is essential to pick up any metastasis if seen in the earliest stage during a follow up ultrasound scan or CT scan. I can see that you have mentioned AST and ALT results but to tell the chances for a liver metastasis the alkaline phosphatase levels are more reliable. If alkaline phosphatase rises more than 12 units in 6 weeks then there is a higher chance of liver metastasis. Please do not worry.