I am 56 year old female with RA, fibro, depression, chronic migraine, well-controlled hypertension, hypothyroidism, and high cholesterol who is morbidly obese. I take Humira, methotrexate inj, prednisone, hydrochloriquine, lyrica, Prozac, Wellbutrin, lithium, synthroid, lovastatin, and benazapril. I recently started buprenorphine sublingual for pain and use Imitrex prn. I have been feeling bloated and using GasX for attempts at relief. Having trouble with nausea and vomited a few times over past week. Wet the bed TWICE in one night this weekend - never happened before. I feel sick and sleep a lot. My eyes are watery and a bit crusty - assume it s the Sjogrens that I also was dxn ed with. Headaches have been constant for two weeks and feel different than normal for me. Is Dr. House out there? I need help to figure out what is going on. Thank you.