I was diagnosed with macular degeneration last Feb. 2015. In May my doctor put me on Mirtazapine. Can this drug adversely affect AMD? My second question is, can this drug cause nightmares? In the past, I rarely even remembered my dreams, but now I usually remember them every morning and beyond. I don t mind the dreams especially, but I also started having terrible nightmares. The nightmares only happen once or twice a month, but they are quite severe, to the point that I wake up feeling terrified and it can take up to hour to calm down.