Hi, As you have mentioned about your husband- 1) Age 47yrs. 2) previous history of gout. (Gout: caused by abnormal deposition of crystals of uric acid in joints mainly of foot, great toe joint. there may be normal or high serum uric acid level.) 3) Kidney malfunction in January. 4) Current ultrasound finding of mild bilateral renal parenchymal disease with significantly raised serum creatinine 803.36 umol/l (normal 80 – 115 µmol/L) and marginally raised serum uric acid level 477.50µmol/L (normal 200– 430µmol/L). 5) Absence of diabetes and high blood pressure. I want to know about - 1) Recent use of nephrotoxic drugs like pain killer medicine. 2) Recent illness. 3) Dehydration due to any cause (loose motions, vomiting, excessive sweating) As all these factors may aggravate underlying mild kidney dysfunction. In current scenario I will advise you to consult nephrologist immediately because- There is Significant elevation in serum creatinine levels and there might be impending need for dialysis. If waiting for nephrologist, do all these investigations - 1) Serum electrolytes,calcium, phosphorus, vitamin D level, blood urea level, urine examination, urinary protein level. 2) Arterial blood gas levels. 3) Chest x ray. 4) Monitor daily urine out put.