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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Bladder Spasms And Constipation?

I take prednisone (10mg, once a day) and plaquenil (200 mg, twice a day). They cause bladder spasms and constipation. The symptoms have been happening for two weeks. But I've been taking the plaquenil for eight months and prednisone for one year. What should I do about it?
Thu, 2 Mar 2017
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General Surgeon,  's  Response
Hi.
Thanks for your query.
Noted the history of taking Prednisone 10 mg a day and Plaquenil 200 mg twice a day. These are causing bladder spasms and constipation, going on for 2 weeks, taking medicines for long as you have mentioned and wants to know what to do?
Since you have been taking Plaquenil for 8 months and Prednisone for one year, these medicines causing such a problem is not a possibility.
Hence I would advise you the following:
Consult an Urologist for proper clinical evaluation, examination and ask for investigations as follows:
Urine: Routine, microscopy, culture and sensitivity.
Tests of blood for CBC, Sugar and thyroid function tests.
Ultrasonography of the abdomen particularly for uro-genital system.
A course of an antibiotic if there is an evidence of infection.
Antispasmodic as indicated.
If no relief, you may need cysto-urethroscopy.
Further evaluation and proper management.
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What Causes Bladder Spasms And Constipation?

Hi. Thanks for your query. Noted the history of taking Prednisone 10 mg a day and Plaquenil 200 mg twice a day. These are causing bladder spasms and constipation, going on for 2 weeks, taking medicines for long as you have mentioned and wants to know what to do? Since you have been taking Plaquenil for 8 months and Prednisone for one year, these medicines causing such a problem is not a possibility. Hence I would advise you the following: Consult an Urologist for proper clinical evaluation, examination and ask for investigations as follows: Urine: Routine, microscopy, culture and sensitivity. Tests of blood for CBC, Sugar and thyroid function tests. Ultrasonography of the abdomen particularly for uro-genital system. A course of an antibiotic if there is an evidence of infection. Antispasmodic as indicated. If no relief, you may need cysto-urethroscopy. Further evaluation and proper management.