Hello As you mentioned that there is burning sensation in the chest with loss of appetite , weight loss , insomnia , antacid ( like prilosac not working) . These symptoms may be due to these reasons , these includes. 1 Tension or anxiety or depression , so please consult a psychiatrist and get his opinion. 2 The next reason of such symptoms may be due to peptic ulcer disease or Hiatus hernia . As symptoms are very sever ,so we can t rule out peptic ulcer if thesalke symptoms are from prolong time . Diagnosis can be confirmed G I endoscopy . Try raising the head of your bed 4 inches with blocks. It also might help to avoid eating or drinking for 2 hours before you lie down. To control stomach acid one should not drink alcohol or drinks with caffeine in them or eat chocolates or spicy or greasy foods . In your case as symptoms are very sever so you may need drugs like REBAMIPIDE 100 mg trice in day for 3 months . This is a prescription drug so consult a physician and get his opinion. 3 As you mentioned that there is white coating over tongue with sore throat so these symptoms may be due to amoebic colitis or ulcer in colon . Diagnosis can be confirmed by physical examination by a physician . Hope this information will be helpful for you. Good luck.