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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated Creatinine Levels While Treating Stage-4 Lung Cancer?

I have stage 4 lung cancer, have had 8 rounds of chemo in 8 months, and it was stopped because of elevating creatinine levels. No kidney damage, despite the cancer in my dead left adrenal gland. Level was 141, had 5 days of hydration, and creatinine came back 144 after hydration drip. What would cause this? Blood pressure is 128/89.
posted on Fri, 18 Dec 2015
Twitter Sun, 31 Jan 2016 Answered on
Twitter Tue, 2 Feb 2016 Last reviewed on
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General & Family Physician,  's  Response
Hi! Welcome to health care magic!

Such fluctuations in creatinine in your case can be due to, either due to decreased hydration or other causes which lead to a decreased blood flow to kidneys or it can also be drug induced. Some chemotherapy medicines can cause kidney toxicity of some grade. You can have ultrasound KUB for renal parenchyma echogeneitcy, kidney sizes and cortical thickness. You may also be asked for urinalysis for any puss cells or red cells in urine. With all these reports consult a nephrologist and meanwhile keep good hydration. Hoping you a speedy recovery. Regards.
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What Causes Elevated Creatinine Levels While Treating Stage-4 Lung Cancer?

Hi! Welcome to health care magic! Such fluctuations in creatinine in your case can be due to, either due to decreased hydration or other causes which lead to a decreased blood flow to kidneys or it can also be drug induced. Some chemotherapy medicines can cause kidney toxicity of some grade. You can have ultrasound KUB for renal parenchyma echogeneitcy, kidney sizes and cortical thickness. You may also be asked for urinalysis for any puss cells or red cells in urine. With all these reports consult a nephrologist and meanwhile keep good hydration. Hoping you a speedy recovery. Regards.