I am 72 yrs old I have cardiac problems of a moderate leaking aortic valve and ascending aortic aneurysm , lymphedema of Legs and feet, pinched nerve in neck along with arthritic spurs and lower back problems with arthritic spurs plus Hypothroidism, COPD Asthma& Obese. In Aug,2013 I developed pinch nerve in neck. Oct lower back went out. Took flexeril & Meloxicam for pain I am currently on Furosemide , Levothyroxine, Losartan, Spironolactone, Nexium, Senna Plus, B-Complex with B12,Vit D3, Fish Oil, Ipratropium Bromide Nasal Spray (as needed) . Dr stopped Metoprolol Succ. Because I complained of extreme tiredness and suffering from extreme muscle and joint pain after doing my normal daily activities Removing the Toporal helped with the tiredness but not the muscle & joint pains I am wondering if the Spironolactone is causing the pain. I take care of my 95 yr old mother as well as cook. Laundry and do some care for 3 grandchildren. We are a family of 7 Before August when I hurt my neck, I had tiredness but no muscle & joint pains Hope you can help. Are there any drug interactions? Carol McBride