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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Greying Of Face After Diagnosed With End Stage Adenocarcinoma Metastasized To Bone Marrow?

My father has end stage non small cell adenocarcinoma, mets to brain and now all bones marrow etc. We do have hospice in so, my question is for curiosity only. Just within the past 2 days, Dad's forehead and face have started to get very gray, ashen if you will. I have tried to research this and can not find my answer. What is causing the graying of his face?

posted on Fri, 14 Mar 2014
Twitter Sat, 16 May 2015 Answered on
Twitter Mon, 18 May 2015 Last reviewed on
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Pathologist and Microbiologist,  's  Response
Hi, I did review your concern. The greying of face that your father is experiencing can be due to a paraneoplastic syndrome in which the cancer cells secrete certain molecules like ACTH and POMC that increases pigmentation in many sites in body as they stimulate pigment producing cells of skin. Your . father can use sunscreen lotion while going out. I hope this helps. Take good care of your father. You are a brave son.
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What Causes Greying Of Face After Diagnosed With End Stage Adenocarcinoma Metastasized To Bone Marrow?

Hi, I did review your concern. The greying of face that your father is experiencing can be due to a paraneoplastic syndrome in which the cancer cells secrete certain molecules like ACTH and POMC that increases pigmentation in many sites in body as they stimulate pigment producing cells of skin. Your . father can use sunscreen lotion while going out. I hope this helps. Take good care of your father. You are a brave son.