I have been battling with joint pain for two years now, and no one can tell me what s going on. My last blood work showed an levated CRP level, and I tested positive for the HLA-B27 gene. In addition, I have a low C3 complement. Lupus and RA blood work came back negative. Bone scan showed no arthritis. The joint pain has worsened and is now in my feet, ankles, knees, hips, fingers, elbows and sometimes my jaws. Fatigue is also a huge problem. Any suggestions or ideas as to what this might be?