What Causes Lower Back Pain And Tiredness?

I am male 56, weigh 210lbs and 1.84m. for the last 20yrs have had lower back issues through work, and damage to my knees. usually managed with pain killers and visits to Osteopath. Last six months I have had severe cramp in lower legs, mainly night time. nothing helps to get rid, feels like my bones breaking its so painful. now followed by tingling, throbbing of calf and more worrying swelling above ankles and when pressed the area of skin doesnt return it leaves indentation until swelling goes down. I have had blood test, for heart, liver, kidney , lungs, results ok. but low on Vitamin D apparently. more recently i have no pressure when urinating, throbbing legs more often and pulsating with lower back pain and tiredness.