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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Necrotizing Granulomateous Inflamation?

IYes, thank you. I had a lymph node biopsy in the crease of the groin area with two enlarged lymph nodes there. It came back as necrotizing granulomateous infection. I had a course of doxycycline and had an ultra sound which says they have decreased. My doctor I see says this needs more investigation. I also go to the pain clinic in Buffalo New York and the Dr/Owner of the clinic talked to me today and recommends I get a second opinion with an oncologist. I told him I was diagnosed with Lyme Disease in 2000 and have had all the effects from that from bad arthritis to bad headaches. I also have been battling Rosacea on my face which is severe at times. My question to him today was are all these things correlated together and that would be my question for you. I would appreciate any help you could give me. Thank you so much.
Fri, 14 Feb 2014
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Infectious Diseases Specialist 's  Response
Hi,

Welcome to HCM.

I understand your concern regarding the groin lymph nodes. Necrotizing granulomatous reaction indicates chronic infection of the lymph node which usually occurs in chronic diseases like tuberculosis, lymes disease, chronic diseases of the groin and perianal regions. I suggest you get a detailed examination done by a GP nearby you to rule out chronic infections of the groin before suspecting malignancy.
Thanks.
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What Causes Necrotizing Granulomateous Inflamation?

Hi, Welcome to HCM. I understand your concern regarding the groin lymph nodes. Necrotizing granulomatous reaction indicates chronic infection of the lymph node which usually occurs in chronic diseases like tuberculosis, lymes disease, chronic diseases of the groin and perianal regions. I suggest you get a detailed examination done by a GP nearby you to rule out chronic infections of the groin before suspecting malignancy. Thanks.