My wife Gail has had rwo urinary track infections in the last month She is on Humira for three months which lowers your immune system She has tingling in her lips and feet , very slight She has discomfort in her abdomen under rib cage She has rheumatoid arthritis She has had an auto immune disease for five years which requires her to be on Methotrexate. She is taking folic acid to offset Doctors appointment is tomorrow