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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Severe Fatigue And Anxiety While On Lisinopril?

I have been on the blood pressure medicine Lisinopril-HCTZ20/25mg for about 2 weeks. I have been extremely tired and have seemingly anxiety attacks which I am not sure what that is all about. Also seems like shortness of breath. So are these symptoms of this medication?
Sat, 3 Nov 2018
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Neurologist,  's  Response
Hello,

Some of the most common side effects of lisinopril (depending upon the specific preparation) are:

cough, dizziness, drowsiness, headache, depression, nausea, vomiting, diarrhea, upset stomach, and mild skin itching or rash.

Other symptoms to the body as a whole include Fatigue, asthenia, orthostatic effects (dizziness or feelings of faintness). Also, depressed mood, hallucinations, and confusion have been reported.

With respect to shortness of breath there is a known side effect of SIADH which causes the release of a chemical substance that causes the body to RETAIN FLUID.

Although not terribly likely as the immediate cause of your shortness of breath there could be an accumulation of fluid buildup in your heart and/or lungs because of this unexpected shift in fluid volumes due to the drug. This is rare.

Since you are reporting these symptoms related to the start of this medications within the past 2 weeks I would definitely have a talk with the doctor and alert them to what's going on. I'm sure they will want to take some action.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr. Dariush Saghafi, Neurologist
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What Causes Severe Fatigue And Anxiety While On Lisinopril?

Hello, Some of the most common side effects of lisinopril (depending upon the specific preparation) are: cough, dizziness, drowsiness, headache, depression, nausea, vomiting, diarrhea, upset stomach, and mild skin itching or rash. Other symptoms to the body as a whole include Fatigue, asthenia, orthostatic effects (dizziness or feelings of faintness). Also, depressed mood, hallucinations, and confusion have been reported. With respect to shortness of breath there is a known side effect of SIADH which causes the release of a chemical substance that causes the body to RETAIN FLUID. Although not terribly likely as the immediate cause of your shortness of breath there could be an accumulation of fluid buildup in your heart and/or lungs because of this unexpected shift in fluid volumes due to the drug. This is rare. Since you are reporting these symptoms related to the start of this medications within the past 2 weeks I would definitely have a talk with the doctor and alert them to what s going on. I m sure they will want to take some action. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr. Dariush Saghafi, Neurologist