My mother is taking several meds and is quite tired. She wants to know if any of these would be causing such fatique,: Promacta 50 mg, Prednisone 5 mg. Metoprolol 50 mg (2x a day) Losartan 100 mg Spironolactone 25 mg Raloxifine 60 mg. She feels loopy and tired and can t function . Frustating as she has been very active 85 years old and recently lost her husband and had a serious fall last August resulting in hospitalization.