Hi Dr,I have been on Anastrozole now for nearly a year. I will be seeing my oncologist in two weeks time. I have been experiencing increased difficulty getting off to sleep each night despite exercise each day and plenty of activity.This has become more of a problem as the year has progressed. Sometimes it is because of hot flushes and joint pain or feet pain, but sometimes it is just for no reason. I can be very tired and yet after I go to bed I seem to wake up just as I want to sleep. I have been prescribed some temazepam by my GP, and I am becoming increasingly reliant upon it. I don t want to have to take it every night but as I work four days a week it helps me be ready for my work day.Any suggestions ? Would it be beneficial to change to time of day I take the tablet ? I always take it at bedtime within an hour of the same time each night.