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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Stomach Discomfort While On Prednisone And Sulfasalazine?

I was just diagnosed with rumatoid arthreistis. The rumatoligist put me on prednisone 20mg an sulfasalazine 500mg. She put me on this mon. I am having stomach issues. I cannot eat a lot. After I eat I cannot seem to do anything without pain in the center of my chest
Tue, 12 Jan 2016
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General & Family Physician,  's  Response
Hi & Welcome.
After having gone through your concerns, I am of the opinion that you have developed acidity related problems of the stomach (gastritis and reflux disease) apparently caused by Prednisone and partly by Sulfasalazine.
Stomach discomfort and reflux issue can be easily be prevented by using certain medications like proton pump inhibitor like Omeprazole or H2 receptor blocker like Ranitidine prior to administration of Prednisone & Sulfasalazine.

Hope this answers your query.
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What Causes Stomach Discomfort While On Prednisone And Sulfasalazine?

Hi & Welcome. After having gone through your concerns, I am of the opinion that you have developed acidity related problems of the stomach (gastritis and reflux disease) apparently caused by Prednisone and partly by Sulfasalazine. Stomach discomfort and reflux issue can be easily be prevented by using certain medications like proton pump inhibitor like Omeprazole or H2 receptor blocker like Ranitidine prior to administration of Prednisone & Sulfasalazine. Hope this answers your query.