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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Sudden Fluctuations In The Cbc Level With A Family History Of Leukemia?

Hi my son had a fever lasting roughly 5 days followed by a rash lasting another 4-5 days the drs were concerned he had measles and took routine blood work this was the first time he had a cbc. His palette levels were moderately low (131) after his measles test came back negativeI was asked to bring him back a week from orioriginal date for another cbc this time his levels were quite elevated (644) is there a concern I should have to these results? Is it normal to fluctuate that high out of normal range in a matter of weeks or is this something I should bring to a blood specialists? There is a strong family history of leukemia should I be concerned about that as well ?
Thu, 4 Sep 2014
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Geriatrics Specialist 's  Response
Hi,
Thanks for asking.
Based on your query, my opinion is as follows.
1. Increased platelets level is good and goes against the diagnosis of leukemia.
2. So much variation is not possible. Get a second test at other lab or get a platelet count on peripheral smear.
3. Along with it, also get a differential leukocyte count to look for immature cells. I would not expect to find anything with normal platelet levels.
Hope it helps.
Any further queries, happy to help again.
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What Causes Sudden Fluctuations In The Cbc Level With A Family History Of Leukemia?

Hi, Thanks for asking. Based on your query, my opinion is as follows. 1. Increased platelets level is good and goes against the diagnosis of leukemia. 2. So much variation is not possible. Get a second test at other lab or get a platelet count on peripheral smear. 3. Along with it, also get a differential leukocyte count to look for immature cells. I would not expect to find anything with normal platelet levels. Hope it helps. Any further queries, happy to help again.