Hi, Thanks for consulting. I have carefully worked through your case, and I can realize your health worries. Being your physician, I assure you not to worry as I will take care all of your medical concerns. The rashes present all over the body indicates allergy to any one of the drugs she s been consuming. You would have to ask your doctor if test dose of penicillin was given, before starting penicillin. Most importantly you need to visit her doctor, in order to stop the allergic drug and treat the allergy with necessary antihistamines. The swelling of her hands and legs is either due to the allergy or other organs like heart/kidney affected by the fever itself. You have to get the following blood tests to detect the cause and treatment. - complete blood count - Renal function test - Electrocardiography to rule out any complications due to previous fever. You do not have worry, as these tests will give a confirmation about the existing problem which can be treated accordingly. She will do great Cheers