I was taking Advair Inhaler for reactive airway disease after a bout of bronchitis. After about 3 weeks I started to develop tiredness and heart fluttering. I saw the pulmonologist the next week and by then I was week tired and my legs were swollen. They did blood work, checked kidney function and did a echocardiogram. They said I was developing a leaky valve. My Advair was decreased to 1 puff twice a day. I still felt lousy and the swelling in my legs had decreased but not completely gone. Finally after about 3 more weeks, I called my pulmonary doctor and told her I was going to discontinue the inhaler. She did not call back until the next day. I told her I had stopped the inhaler for a day and a half and already I was feeling more energetic and legs were not as swollen. I think that Advair caused my heart valve problem and it seems like it did something to the conduction of my heart, like it doesn t pump or beat as strong. Has this been reported before?