Hello Thanks for writing to HCM Non specific ischemic foci in both cerebral hemispheres with few old lacunar infarcts in bilateral basal Ganglia are mainly due to chronic microvascular ischemic changes resulting from involvement of small blood vessels. Iischemic changes resulting from blood vessels changes in diseases like hypertension,diabetes mellitus,dyslipidemia. So,your father need monitoring of conditions that leads to ischemic changes like hypertension,altered lipid profile,diabetes mellitus. He need investigations like routine hemogram,RBS,LFT,RFT,Lipid profile,ultrasound of abdomen. Cerebral cortical atrophy is age related finding and doesn t require any treatment. Hope i have answered your query. Take Care Dr.Indu Bhushan