Hi there, Welcome to HCM, At 7 weeks scan every thing looks as expected. And the doctor is right in suggesting a NT scan and blood tests at 13 weeks. Since she was on anti depressant medications for 3 years, it is not wise to discontinue them suddenly without any medical advise. She should consult her psychiatrist who will advise her if she can safely discontinue or not. Also other forms of therapy for depression like cognitive behavioral therapy should be offered to her. Pregnancy is a stressful time and her depression could get worse if she doesn t get appropriate medical help. Drugs could affect pregnancy and women who have taken anti depressants have a slightly 1% more chances of having babies with birth defects. These are easily checked by both NT scan and 20 week anomaly scan. So do not worry a lot about them. I would recommend her to take Folic Acid 5 mg at least till 12 weeks. Though its more important to take it before conception it is still advisable to continue it till 12 weeks. Depression is also more common post delivery and this should be kept in mind after delivery especially if she has baby blues and mood swings then. Please inform this to the doctor managing her post delivery. Hope this helps. Regards.