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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does Occlusive Disease Mean?

hello, I recently read that deficiency of factor XII is good news for someone because Factor XII selectively contributes to thrombus formation in occlusive disease, but not to normal hemostasis I would be very grateful if you write me which are the occlusive disease??
Tue, 28 Feb 2017
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Cardiologist 's  Response
Hi There

Factor XII also known as HAGEMAN Factor. Studies have shown that its deficiency rarely produces any symptoms because it is compensated by other clotting factors.
So if it is deficient in a person then he or she will be less prone to develop occlusive diseases of the venous system like DEEP VEIN THROMBOSIS, PULMONARY VENO OCCLUSIVE DISEASE (causing pulmonary hypertension), HEAPTIC VENO OCCLUSIVE DISEASE.

Good Luck
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What Does Occlusive Disease Mean?

Hi There Factor XII also known as HAGEMAN Factor. Studies have shown that its deficiency rarely produces any symptoms because it is compensated by other clotting factors. So if it is deficient in a person then he or she will be less prone to develop occlusive diseases of the venous system like DEEP VEIN THROMBOSIS, PULMONARY VENO OCCLUSIVE DISEASE (causing pulmonary hypertension), HEAPTIC VENO OCCLUSIVE DISEASE. Good Luck