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What Does This Test Result From Widal Test Indicate?
Does it mean that if i have widal test of salmonella typhi O = 160 and salmonela typhi H =160,salmonella paratyphi AO = 160,salmonella paratyphi BO = 20,salmonella paratyphi CO = 20,salmonella paratyphiAH =80,salmonella paratyphi BH = 20 and salmonella paratyphi CH = 20,that i have typhoid.
Thu, 13 Aug 2015
Hi & Welcome to HCM.
Incomplete data like timing of taking the blood sample, any treatment like antibiotic given and the associated symptoms.
After having gone through the results of the Widal test, I am of the opinion that the Widal test is positive for Typhoid.
However, this result needs to be correlated clinically;
1. A single Widal test is of little clinical relevance due to a number of cross reacting infections, including malaria. If no other tests are available, a 4 fold increase in the titer (e.g., from 1:40 to 1:160) in the course of the infection, or a conversion from an IgM reaction to an IgG reaction of at least the same titer, would be consistent with a typhoid infection.
2. Patients who have received vaccines against Typhoid may give false positive reactions. This can be differentiated from true infection by repeating the test after a week. True untreated infection results in rise in
titre whereas vaccinated individuals don’t demonstrate any rise in titre
3. Those individuals, who had suffered from enteric fever in the past, sometimes develop anti-Salmonella antibodies during an unrelated or closely related infection. This is termed anamnestic response and can be
differentiated from true infection by lack of any rise in titre on repetition after a week.
Hope to have given a clarification regarding the results of given Widal test.
A feed back is appreciated.
Incomplete data like timing of taking the blood sample, any treatment like antibiotic given and the associated symptoms.
After having gone through the results of the Widal test, I am of the opinion that the Widal test is positive for Typhoid.
However, this result needs to be correlated clinically;
1. A single Widal test is of little clinical relevance due to a number of cross reacting infections, including malaria. If no other tests are available, a 4 fold increase in the titer (e.g., from 1:40 to 1:160) in the course of the infection, or a conversion from an IgM reaction to an IgG reaction of at least the same titer, would be consistent with a typhoid infection.
2. Patients who have received vaccines against Typhoid may give false positive reactions. This can be differentiated from true infection by repeating the test after a week. True untreated infection results in rise in
titre whereas vaccinated individuals don’t demonstrate any rise in titre
3. Those individuals, who had suffered from enteric fever in the past, sometimes develop anti-Salmonella antibodies during an unrelated or closely related infection. This is termed anamnestic response and can be
differentiated from true infection by lack of any rise in titre on repetition after a week.
Hope to have given a clarification regarding the results of given Widal test.
A feed back is appreciated.
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