Diet for hepatosplenomegaly A tea made from apple tree bark can cleanse the lymphatic system and shrink an enlarged spleen. Also, apple cider that has been boiled down to syrup, taken by the tablespoon as a tonic, can ease an enlarged spleen. A milk thistle supplement, in the form of a capsule or tablet that you can purchase at your local health food store, supports liver and spleen function. The two organs work closely together, and an enlarged spleen is often caused by an overworked liver. A diet high in fruit, along with plenty of water, will help keep the lymphatic system clean. Increase intake of high-fiber fruits such as apples, bananas and blueberries. Foods to Eliminate : When suffering from an enlarged spleen, avoid fatty and processed foods. These foods are difficult to digest and put significant strain on the liver and spleen, Alcohol : The spleen and liver are dependent on each other for proper function. An overtaxed liver can lead to an enlarged spleen. Cut out alcohol and increase water intake to shrink a spleen. Regards Dr De