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Proposed treatments for Leber's Hereditary
optic neuropathy (LHON) include low vision aids, avoidance of potential precipitants of visual loss, general therapies for mitochondrial disorders, anti-apoptotic agents and a variety of gene therapies.
Avoiding
optic nerve toxins is generally advised, especially tobacco and alcohol
Symptomatic treatments should be considered in all patients with vision-impairing optic neuropathies to improve quality of life.
General therapies that have been suggested for the treatment of
mitochondrial disease include:
1.vitamins and cofactors [
coenzyme Q10 (CoQ10), folic acid, vitamin B12, thiamine, riboflavin, l-carnitine, l-arginine and creatine],
2.free radical scavengers (CoQ10, idebenone, alpha-lipoic acid, minocycline,
cyclosporine A, glutathione and vitamin E);
and inhibitors of toxic metabolites (dichloroacetate).
Feel free to ask if you have any other query
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