Hello dear, Thank you for your contact to health care magic. I read and understand your concern. I am Dr Arun Tank answering your concern. E.coli is the bacteria present as a commensal flora of the skin, and mucus membrane of the body. Its infection can occur when the body situation is not favourable. In your condition it is the chronic bedridden state that has compromised the immunity status of yours. In my advice you should take the sensitivity report of the e coli done. Taking the drug according to the report can cure you on good time and also cures you with minimal antibiotic use. Please maintain good local hygiene this can be done by proper cleaning and dressing of the affected part. You can do good dressing with the use of betadine, savlon and polysporin ointment. Please give high protein, low fat and high carbohydrate diet. Avoid more oily and spicy food. I will be happy to answer your further concern on bit.ly/DrArun. Thank you, Dr Arun Tank Infectious diseases specialist, HCM.