Sir,

My wife, a post operative case of CA Colon in 2003 and CA Endometrium in 2006 has now been diagnosed as a case of CA Colon (Transverse Colon). The PET Scan report indicates (a) Abnormal focal increased FDG uptake noted in solitary right axillary lymph node (SUV Max 6.3) (b) Focal abnormal FDG uptake seen at ileo colic anastomic site (SUV 10.2) (c) Abnormal increased FDG uptake in bilateral adrenal glands, right more than left (SUV Max right 7.8, left 4.2) (d) Abnormal increased FDG uptake in serosal deposits along ileal loops (SUV Max 10.6) and discrete mesenteric nodes (SUV Max 8.0) (e) Diffuse increased FDG uptake seen in multiple vertebrae, bilateral ribs, proximal parts of humeri & femorii (SUV Max 5.4) (f) CT detected non enhancing hypodense lesion in left postero lateral wall of rectum and bilateral lung nodules show no abnormal FDG uptake. (g) Normal physiological FDG uptake seen in brain, pharyngeal tonsils, vocal cords, myocardium, liver, rest of intestinal loops, kidneys and urinary bladder. She is now lean, with loss of appetite, less stool passing, vomiting temptation and pain while taking liquid or solid food. The treating oncologist/surgeon has overruled the possibility of surgery and advised chemotherapy. May I have your expert advice on best possible curative treatment.