Hello, Welcome to HCM, The pain in case of herpes can be reduced and treated by If fever blisters erupt, they should be kept clean and dry to prevent bacterial infections. A bland diet is recommended to avoid irritating the sores and surrounding sensitive areas. Avoid touching the sores and spreading the virus to new sites, such as the eyes and genitals. Prevent infecting others it is important to wash hands after eating or touching one’s mouth. Ice applied directly to the cold sore site prior to the eruption of a blister. Wrap an ice cube in a damp cloth and keep it on the area for five minutes. Oral acyclovir lessen the symptoms and frequency of fever blister recurrences for some patients. Topical antiviral creams may also help in limiting the extent or duration of lesions if applied promptly to affected areas. Lidocaine skin patches Capsaicin is available as a low-concentration cream can improve pain. Gabapentin an anticonvulsant to help control burning and pain. Antidepressants for postherpetic neuralgia in smaller doses than they do for depression alone. These are some of the remedies and drugs used in controlling and management of pain following the herpes infection. Thank you.