hi,there i wil strongly advise you against taking any medicine without consultation with your doctor,self medication should never b done. the side effects of primolu nor drug are: Headache (including migraine headache) Feeling sick Being sick Stomach ache Swollen or sore breasts Change in weight Changes in sex drive Patches of darkened skin Itching Acne Rash Change in appetite Feeling dizzy Feeling tired Feeling depressed Breakthrough bleeding or spotting from the vagina Irregular menstrual periods High sugar levels in the blood Difficulty sleeping Confusion Feeling nervous Constipation Diarrhoea Dry mouth Blood clots Fever Eye problems Increase in body hair Worsening of migraine headaches Worsening of fitting (epilepsy) Liver tumours. this drug should not b used before surgery and if you are using this drug then inform your anesthesiologist and surgeon that you r taking this drug i hope i have answer your query. if you hv any other query i wil b glad to help. wish you best of health. thanks