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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will The SGPT Will Go Back To Normal If Lipitor Is Stopped?

Due to elevated cholesterol of 6.58, LDL of 4.64, SGPT of 33.59, I was put on simvastatin 20mg (vidastat) for 2 months. However, after 2 months, the simvastatin did not seem to work, my cholesterol and LDL further increased to 7.52 and 5.12. But SGPT was down to 28.97. I was shifted to Lipitor 20mg. After 2 and 1/2 months of taking it, cholesterol (4.69) and LDL (2.77) became normal. BUT FBS now elevated to 5.72 and SGPT soared to 45.33! I am so worried that liver may have been damaged. Do I need a liver ultrasound? Should I start taking Essentialle Forte or Silymarin? Should i also start Metformin Glucophage XR 750mg, at leat for a month, to arrest any liver or sugar level problems. I am currently on maintenance meds for hypertension (micardis 40mg in the morning, and norvasc 5mg in the evening). I am also overweight by 25-30 lbs. I am 44 years old, female. If i stop the lipitor, will my SGPT go back to normal? Thank you very much.
Wed, 27 May 2015
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Internal Medicine Specialist,  's  Response
Hello,

First of all, your sgpt elevation is not that worrisome. It's not even the double of the highest normal value. Sgpt values lower than three times the highest normal value are considered acceptable.

Since you're overweight you should do a liver ultrasound which may reveal fatty liver changes. Fatty liver itself may cause liver tests elevation particularly if you had gained weight recently.

If your doctor considers lipitor as the cause of thebhigh sgpt then you should do a repeat measurement after a week or so to make sure it won't get any higher and you can continue to take it afterwards.

There is no need to take anything. You can try to loose some weight which will help you with a potential fatty liver and with the cholesterol as well.

I hope I've helped!
You can contact me again if you'd like any clarification or further information.

Kind regards!
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Will The SGPT Will Go Back To Normal If Lipitor Is Stopped?

Hello, First of all, your sgpt elevation is not that worrisome. It s not even the double of the highest normal value. Sgpt values lower than three times the highest normal value are considered acceptable. Since you re overweight you should do a liver ultrasound which may reveal fatty liver changes. Fatty liver itself may cause liver tests elevation particularly if you had gained weight recently. If your doctor considers lipitor as the cause of thebhigh sgpt then you should do a repeat measurement after a week or so to make sure it won t get any higher and you can continue to take it afterwards. There is no need to take anything. You can try to loose some weight which will help you with a potential fatty liver and with the cholesterol as well. I hope I ve helped! You can contact me again if you d like any clarification or further information. Kind regards!