yes, I had to take prednisone for 6 days and went from 6 pills down to one and now, I am noticing a little menstrual blood and I have not had a period in 12 years. I am having back pain like I used to when I had a menstrual period. Is this due to the prednisone? I had to take it because the dr said my body had came in contact with something it did not like and I got a very itchy rash on my neck and face.