LGIB is common is the elderly than in younger people because diverticulosis and malingant of colon are more common in these groups.
Causes of LGIB
- Colitis- Ischemic colitis, ulcerative colitis, radiation induced colitis
- Infection colitis with E- coli, shigella, C. difficle, Campylobacter jejuni
- Non infectious colitis (idiopathic) Like Crohns or ulcerative colitis
- Anorectal disease- hemorrhoids, fissures and fistulas
- Diverticular disease- diverticulosis, diverticulitis
- HIV related opportunistic infection- CMV colitis, Kaposi sarcoma and lymphoma
- Drug induced bleeding- Aspirin and anticoagulants
- Vascular- Angiodyplasia, polyarteritis nodosa, Wegener’s granulomatosis, and aortocolonic fistulas
- General causes: Salicylates, alchohol, liver failure, renal failure, Ingestion of steroids and NSAID's.
- Small intestinal causes: Intussusceptions and Meckel’s diverticulum
- Neoplasm- Colon cancer, postpolypectomty bleeding
Signs and symptoms
- Rectal bleeding
- Blood in the stools
- Blood on the toilet paper
- Pallor
- Shortness of breathe
- Weakness
Tests and diagnosis
- Complete blood count
- Serum electrolytes
- Renal function test (blood urea and serum creatinine)
- Coagulation profile (Prothrombin time and INR)
- Colonoscopy
- Radionuclide Imaging
- Angiography
- Upper GI endoscopy and enteroscopy
Treatment
Medication: Posterior pituitary hormones – Vasopressin and Terlipressin
Modern endoscopic techniques such as injection sclerotherapy, thermo coagulation and laser coagulation seem to be effective in achieving hemostasis and avoiding precarious surgery.
Indications for surgery
- Persistent hemodynamic instability with active bleeding
- Persistent, recurrent bleeding
- Transfusion of more than 4 units packed red blood cells