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Biopsy Report Shows Reactive Gastropathy, Silver Stain Negative For H. Pylori. What Does This Mean?

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Posted on Thu, 18 Jul 2013
Question: Can you please explain in detail what all this means on my report.
A. Biopsy, Gastric Antrum
Reactive gastropathy, silver stain negative for H. pylori.
B. Biopsy, Mid-Esophagus
Hyperplastic squamous and inflamed cardiac mucosa with reactive/hyperplastic changes consistent with gastroesophageal reflux, negative for specialized intestinal metaplasia. Negative for eosinophilic esophagitis. There are no eosinophils present. PAS stain negative for Candida in this sampling. I know this is benign but I also thought hyperplastic changes can have something to do with cancer. Is this something that should be followed up on? If you can please explain what this means in more detail I would greatly appreciate it. Thank you kindly.
Sincerely,
XXXXX
doctor
Answered by Dr. Abhijit Deshmukh (1 hour later)
Hi XXXXXXX
Thank you for the query.
1) Your gastric biopsy suggests that there are mild inflammatory changes (swelling) in the inner lining of the stomach which mean that because of the acid there is mild swelling of the inner lining. This is a fairly common finding which usually need only antacids to treat it and this swelling is inconsequential most of the times. Hpylori is an bacteria which can cause such inflammation and some times ulcers in stomach is negative in the biopsy, which is good.

2) Your esophagus is having mild acid reflux into it from the stomach causing inflammation (swelling) in its lining too. Hyperplastic changes are its consequence and they do not suggest any cancerous change or any risk for same and may disappear after medications to suppress acid and reflux.
I do not think you need to follow them. Eosinophils are seen in diseases like allergic (food ) related problems. You do not have them in biopsy.
So do not worry.
Hope this answers your query.
Wish you a speedy recovery.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Abhijit Deshmukh (1 hour later)
Thank you for clarifying that for me, I do appreciate it.
Sincerely,
XXXXX
doctor
Answered by Dr. Abhijit Deshmukh (10 hours later)
Thank you
Best wishes..
Note: Revert back with your health reports to get further guidance on your gastric problems. Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Abhijit Deshmukh

Gastroenterologist

Practicing since :2001

Answered : 597 Questions

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Biopsy Report Shows Reactive Gastropathy, Silver Stain Negative For H. Pylori. What Does This Mean?

Hi XXXXXXX
Thank you for the query.
1) Your gastric biopsy suggests that there are mild inflammatory changes (swelling) in the inner lining of the stomach which mean that because of the acid there is mild swelling of the inner lining. This is a fairly common finding which usually need only antacids to treat it and this swelling is inconsequential most of the times. Hpylori is an bacteria which can cause such inflammation and some times ulcers in stomach is negative in the biopsy, which is good.

2) Your esophagus is having mild acid reflux into it from the stomach causing inflammation (swelling) in its lining too. Hyperplastic changes are its consequence and they do not suggest any cancerous change or any risk for same and may disappear after medications to suppress acid and reflux.
I do not think you need to follow them. Eosinophils are seen in diseases like allergic (food ) related problems. You do not have them in biopsy.
So do not worry.
Hope this answers your query.
Wish you a speedy recovery.