Question: I am in touch with you since last 3weeks. I am OK. I received your mail Sir. At present I have got 3 questions, pl.advice. 1)Out of last 5 yrs , 4 & ½ yrs daily nite I used to take oleanz 10 mg then next 3months I took oleanz 5 mg. at present I am taking since last 3months oleanz 2.5 mg. With that I take BupronSR 150 x2(LAST 5YRS) & Nexfolin (2 WEEKS) & Peroxtine 20 (4 DAYS) Should I stop oleanz 2.5mg pl.advice. 2)Some time in a day or usually after I am off the bed I feel empty….is there any solution for that.. 3)Sleep deprivation will acts like a antidepressant..I READ MAY BE IN MEDICNE.NET JOURNAL . IT AS FOLLOWS. PL.GO THROUGH AND ADVICE Anyone who is depressed should try it for themselves, and see if they benefit or not. There are two methods of using sleep deprivation as a treatment for depression: total or partial deprivation. Partial deprivation; sleeping the first half of the night only, and waking up halfway through, proved more effective than going to sleep later, or sleeping only the second half of the nightIt is thought that partial sleep deprivation, sleeping up to 4 hours a night, will have the same antidepressant benefits as total sleep deprivation. Whereas with total sleep deprivation, the benefits are felt the following day, but are not long-lasting, sleeping four hours can be done continuously, over several days or even weeks, so naturally the benefits here are superior. If you know someone suffering with severe depression, who barely has energy to talk to you, and no matter how you try to animate them, you have no success, try visiting them in the evening and keeping them awake all night. You will find the next morning their mood will be elevated, they will be more lucid and talkative, and more likely to want to move around and do things The optimum time for sleep appears in some studies, to be from 10pm-2am, 11pm-3am, or12-4 am, underlining the fact that sleeping only the first half of the night provides the best results. In other reports, however, 2-6am 3-7am was optimal. Sleep deprivation treatment was popular in the 1970s, but with the discovery of new and effective antidepressant medications, it was soon deemed old-fashioned and unhelpful. Thanks for this article! I found this so interesting. I've been struggling with depression recently and everyday I felt that it would be impossible to get out of bed and do anything. I'm feeling really good though after a night of not sleeping at all, which seemed surprising. A search on sleep deprivation (which I thought could only have negative effects) lead me to find this. I really want to give this a go now. I'm just wondering, can it be sustained indefinitely without any side effects? I always thought I was the type of person who needed lots of sleep, but maybe that just creates more depression?! I'm also curious about any more findings on this!