Question: Hello, I saw a nurse practitioner yesterday to address an issue I am having with the little toe on my right foot. 5 days ago, experienced intense, painful itching/burning all over that toe, including the top of foot area just above the toe. 3 days ago, developed large, flat white blister between little toe and 4th toe, intermittent burning pain, accompanied by swelling. Suspected fungal infection, and attempted to treat with antifungal cream I had on hand; seemed to have no effect. Yesterday morning, toe was extremely swollen and numb (still itchy, and feels like someone tied a string around the base of toe too tightly) and difficult to move so I sought medical help. Nurse practitioner examined and said did not look like athlete's foot (confined to area of one toe only), but said she had never seen anything like it (mentioning that by just visually looking at my foot, my toe appeared so swollen that she would have assumed it broken). She discovered 2 additional blisters immediately underneath the toe (that I could not see). Diagnosed my issue as possible allergic reaction to insect bites and recommended I take an antihistamine, use an antihistamine cream, and ice the toe (thinking the numbness was related to the swelling), following up if no improvement. More than 24 hours later, the itching seems somewhat less, but the icing seems to be having no effect on the swelling, the numbness in the toe continues, and the white blisters have gotten larger, with mildly red discoloration spreading to the top of my toe. I have had a bad reaction to a spider bite in the past -- any idea what this could be? Thank you very much!