
How Accurate Is HIV Ab1/2 Blood Test At 87 Days From Possible Exposure? Have Negative Results

Thanks for query.
Antibodies against HIV 1 & HIV 2 are usually not detectable until 6-12 weeks of exposure & almost always detectable by 12 months.
PCR RNA test look directly for the genetic material of HIV. There is no accuracy after 21 days of exposure but this test will able to detect it at 15 days & its accuracy is 99.6% after 12 weeks or 84 days of exposure.
Log 10 viral load test is more interpretive when patient is on treatment.
The positive XXXXXXX test 1:1280 has very less say somewhat relation with HIV infection but usually it is more indicative for auto immune disease.
If we go in to symptoms you have abdominal pain & the investigation reveals it as small bowel inflammation.
Look,
The first & foremost symptom of HIV infection is repeated infection. That is missing in your case.
This infection lowers your immune system cause your body to catch infection easily so you have repeated infection that is absent in your case.
Your test result also confirms negative result.
So, nothing to worry about accuracy of test. It is always accurate but more accurate is symptoms.
None of your symptoms mention above related to infection.
Forget about your HIV infection & return to your 20''s.
If you have any query you should feel free to contact me.
Thanks.


Took an EKG test and didn't see anything abnormal but did send me to wear a Holter for 24 hrs. to monitor heart activity.Everything with my heart checked out okay. XXXXXXX 11th,2012 wed. The Hematologist called to say the blood looks good but the platelets dropped again for the 3rd test in a row,down to 45,0000 from 50,0000 and the HIV ab1/2 blood test was negative. I looked at a past history of my platelets from 3 yrs. ago and they were in normal range at 189,000. XXXXXXX 16th 2012 , I went in for a bone-marrow biopsy which checked out okay. Then more blood work for Hepatitis Test and a Viral Load quantitative RNA test for HIV. Results came back non reactive on all but the platelets remained at 45,000. XXXXXXX 20th 2012 fri. My joints have been sore for sometime and my neck is a little stiff. It also became difficult to walk at times XXXXXXX 30th tues. I went to GI Dr for an Upper GI. (I had seen him in XXXXXXX 2011 for an unrelated colonoscopy due to my father having a small amount of colon cancer).Everything looked fine with me then. My results were negative and my scope was as well.Feb 15th 2012 my Platelets went up for the first time from 45,000 to 54,000. March 15th 2012 thurs. Platelets up again from 54,000 to 60,000. April 13th 2012 results down from 60,000 to 57,000. Sun April 22nd my hands and feet are starting cause pain on the bottoms of both feet (in the arches).This is still continuing today and has been about 4 months now.May 15th 2012 tues. I went to see my Family Dr. about the mild pain in my hands but a lot more painful in my feet & He ordered more blood work. I tested Positive XXXXXXX 1:1280, Low Vitamin D (22.3), and platelets slight drop again from 57,000 to 55,000. I went to the Rheumatologist for more blood and urine test. In addition to all the symptoms above, i then noticed what appeared to be little red bumps on my tongue and the right side of my jaw was starting to ache a bit.I have a few bumps on the sides of my tongue that started to appear around early XXXXXXX My b12 normal,metabolic normal, thyroid normal, Rheumatoid arthritis negative. He did test for Lupus and Lyme disease which came up negative. He said the other blood looked good. I do have an uncle and cousin that has MS. My platelets have remained low between 30,000 and 64,000, I was very fatigued and taking afternoon naps cause the lack of energy.Sometimes i feel that I have to think about recent events more than usual. My memory at times is a little foggy. Occasionally my neck and back get stiff.
I'm 44 and felt like i was still in my 20's until that one night in Nov.out to dinner. Everything has gone down hill since that night. I'm not sure if something with the food could've triggered something that is the cause of this? It just seems odd that I felt great and 20 yr.'s younger with no medical history at all,then all the sudden i woke up in severe abdominal pain a few hrs after a late steak dinner. From that point on i went from no history to now carrying a folder full of test files over the past 9 months.Just to recap, my platelets have been in the 40k-64,000 range. I have not noticed any fever,NO skin rash,NO weight change,No night sweats ,No loss of appetite.No Swollen Lymph Nodes.My stomach has been causing a mild belly ache the past few weeks that just feels a little off.I was retested for my XXXXXXX which this time came back 15. When I had the HIV 1/2 AB screen at 87 days since possible exposure that came back NONREACTIVE result and an HIV RNA Quantitive HIV PCR Quant,Log 10 Hiv and the results came back Not Detected. This test was 94 days after possible exposure.What generation are those tests and how ACCURATE are they?? Thank You, XXXXXXX
Thanks again,
The HIV tests are 99.6% accurate as I have mentioned earlier.
I have gone through your detailed history, but it is silent about your exposure to HIV. The food you consumed definitely doesn't expose you to HIV infection. HIV is transmitted through body fluids (blood and genital secretions) of an individual infected with HIV. When these secretions come in contact with tissues such as those lining the vagina or penis, anal area, mouth, eyes (the mucus membranes), or with a break in the skin, etc., HIV may be transmitted.
Regarding the abdominal pain, t is been told by your gastroenterologist that you have small bowel inflammation - causes vomiting & loose motion. The symptoms of bowel inflammation can be recurring and bloody stools are also common.
Now we come to your constant low platelet count; based on the test it seems to be related to a connective tissue disorder say autoimmune disease. Positive XXXXXXX result is an indicator. But as you have no symptoms of your low platelet count like easy bruising or bleeding through bowels / nasal cavity or other orifices, the low platelets are not life threatening. So we may proceed evaluation the causes of low platelet (if there are any others); but as far as HIV is concerned, the results are accurate.
Hope this answers your query.
Regards


Thanks for writing back.
The exposure has taken place roughly in last week of Aug 2011 or starting of Sep 2011.
Usually antibodies were produced within 3 weeks post exposure but they become detectable by four or six weeks after HIV infection. This four to six week period is known as a window period.
To detect it within window period there is a test which is called the Polymerase Chain Reaction (PCR), which can detect the presence of HIV by studying the genetic composition of all the components of the blood.
Once the antibodies were formed it is always detectable in your blood.
That shows negative result in your case.
The most important is symptom.
Your present symptoms favour autoimmune disease.
We should not be rigid too much for 12 months to be completed. I think by this time you should get antibodies if you are exposed.
Thanks.


Hi,
Thanks again,
The probable reason of vomit & diarrhea about 36 days after possible exposure is small bowel inflammation as confirmed by CT scan and not due to HIV infection per se.
HIV antibodies if present usually are detected after 4-6 weeks of exposure. 87 days post exposure is not considered early by most clinician and if antibodies are present at that time, the test would have picked it. The symptoms you have are not related to HIV infection.
The positive XXXXXXX is due to your auto immune disease & symptoms associated with it suggest the first possibility is of ITP of auto immune aetiology. Usually auto immune disease is slow growing life long lasting effects. The titre may be fluctuating depends upon the disease deepness.
If this clarifies all your doubts we may terminate the discussion here. Do rate my answer if you are satisfied with this discussion.
Regards

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