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Is There Interaction Between Sumatriptan And Fluoxetine?

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Posted on Mon, 1 Aug 2016
Question: I have a shocking head ache from my neck being out. A friend suggested I take half a sumatriptan but I do take 1 x fluoxetine 20mg for menopause daily
You advise would be appreciated
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Answered by Dr. Muhammad Ali Rauf (1 hour later)
Brief Answer:
Both together can cause dangerous interaction; close monitoring required.

Detailed Answer:
Hello

My name is Dr Muhammad Ali Rauf & i will look into your problem.


I have gone through your query and would try to help you in the best possible way. Sumatriptan and fluoxetine both increases serotonin levels (an important hormone that controls a number of important functions including cardiovascular system) in the body which can cause potential dangerous interaction due to which reason doctors give both only on close observation. I would suggest you NOT to take both together without discussing with your treating doctor first.

Hope I have answered your query. If you have any further questions I will be happy to help if not then don't forget to close the discussion and rate it.
Wishing you good health !!
Above answer was peer-reviewed by : Dr. Nagamani Ng
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Answered by
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Dr. Muhammad Ali Rauf

General & Family Physician

Practicing since :2013

Answered : 1312 Questions

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Is There Interaction Between Sumatriptan And Fluoxetine?

Brief Answer: Both together can cause dangerous interaction; close monitoring required. Detailed Answer: Hello My name is Dr Muhammad Ali Rauf & i will look into your problem. I have gone through your query and would try to help you in the best possible way. Sumatriptan and fluoxetine both increases serotonin levels (an important hormone that controls a number of important functions including cardiovascular system) in the body which can cause potential dangerous interaction due to which reason doctors give both only on close observation. I would suggest you NOT to take both together without discussing with your treating doctor first. Hope I have answered your query. If you have any further questions I will be happy to help if not then don't forget to close the discussion and rate it. Wishing you good health !!